A Novel Homozygous Mutation in the EC1/EC2 Interaction Domain of the Gap Junction Complex Connexon 26 Leads to Profound Hearing Impairment

Figure 1

Pedigree of the family: patients are carriers of the homozygotic mutation (II-3 and II-6) (black); parents of the patients are each carrier of the heterozygotic mutation (I-2, I-4, and I-5) (half black). (*) Members of the family are also hearing impaired, but the clinical course indicates other causes (grey and half grey); (⁺) no genetic material was available; (?) no information available.