Table 2: Characterization of the MAbs raised against recombinant CA XII: summarized data.

Reactivity with CA XII:
MAb clone    Cross-reactivity of the MAbs with     recombinant CA isoformsIgG subtypeApparent , expressed in E. coli expressed in mammalian cells in cancer cells or tissue
CA ICA IICA VIICA XIIIELISAWBELISAWBFACSIHC

1D5IgG12.07 × 10−10++
4A6IgG11.07 × 10−9++++−/+
5D2IgG15.45 × 10−10++
8C9IgG11.88 × 10−10++−/++
9A8IgG16.17 × 10−10++++
13F5−/+−/+IgG11.12 × 10−10++−/++
15A4IgG2a2.02 × 10−10++++++

“+”: strong reaction, “−/+”: weak reaction, “−”: no reaction.