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BioMed Research International
Volume 2014, Article ID 313252, 7 pages
http://dx.doi.org/10.1155/2014/313252
Research Article

Identification of a Chicken Anemia Virus Variant-Related Gyrovirus in Stray Cats in China, 2012

1College of Animal Science, South China Agricultural University, Wushan Road, Tianhe District, Guangzhou, Guangdong 510642, China
2College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China
3State Key Laboratory of Biocontrol, College of Life Sciences, Sun Yat-Sen University, Guangzhou 510006, China
4Key Laboratory of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture, Guangzhou 510642, China

Received 14 October 2013; Revised 25 December 2013; Accepted 27 December 2013; Published 13 February 2014

Academic Editor: Marcelo A. Soares

Copyright © 2014 Xinheng Zhang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The chicken anemia virus (CAV), is a known member of the genus Gyrovirus and was first isolated from chickens in Japan in 1979. Some reports have also demonstrated that CAV can be identified in human stool specimens. In this study, a variant of CAV was detected using PCR with CAV-based primers in fecal samples of stray cats. The genome of CAV variant was sequenced and the results suggest that it could be a recombinant viral strain from parental CAV strains JQ690762 and AF311900. Recombination is an important evolutionary mechanism that contributes to genetic diversification. These findings indicate that CAV variant might have originated from CAV-infected chickens. The epidemiology and pathogenesis of this novel virus remains to be elucidated. This study underscores the importance of CAV surveillance and it presents the first evidence suggesting the possibility of CAV homologous recombination in cat.