Comparison of Long Noncoding RNA and mRNA Expression Profiles in Mesenchymal Stem Cells Derived from Human Periodontal Ligament and Bone Marrow

Figure 3

The interaction network of significant pathways (Path-net) in stem cells. Pathways that were significantly different between PDLSCs and BMSCs were connected in a Path-net diagram to show the relationships between these pathways. The role of each pathway in the network was measured by counting its connections to upstream and downstream pathways, known as in-degree (upstream connections), out-degree (downstream connections), or degree (all connections). A high degree pathway indicated that it regulated or was regulated by many other pathways, which implied an important role in the signaling network. The circles represent the pathways; blue represents downregulated pathways, red represents upregulated pathways, and yellow represents up- and downregulated pathways. The lines indicate interactions between pathways.