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BioMed Research International
Volume 2014, Article ID 319534, 7 pages
http://dx.doi.org/10.1155/2014/319534
Research Article

Improved Variant Calling Accuracy by Merging Replicates in Whole-Exome Sequencing Studies

Yanfeng Zhang,1 Bingshan Li,2 Chun Li,3 Qiuyin Cai,1 Wei Zheng,1 and Jirong Long1

1Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37203, USA
2Department of Molecular Physiology and Biophysics, Center for Human Genetics Research, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
3Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, TN 37232, USA

Received 28 May 2014; Revised 15 July 2014; Accepted 15 July 2014; Published 4 August 2014

Academic Editor: Ernesto Picardi

Copyright © 2014 Yanfeng Zhang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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