Research Article
Improved Variant Calling Accuracy by Merging Replicates in Whole-Exome Sequencing Studies
Table 1
Summary of WES samples divided into two groups (H and L).
| | Group | Total reads (×106) | Mapping rate (%) | Target mapping (%) | Mean deptha | Mapping rate with MQ < 10 (%)b | Mapping rate with MQ ≥ 20 (%)b |
| | H | 64.0 (49.2–97.9) | 98.2 (95.9–99.2) | 49.7 (46.6–55.4) | 43.4 (34.2–65.8) | 10.4 (9.5–11.3) | 86.2 (84.0–87.7) | | L | 57.2 (40.3–79.3) | 98.7 (97.6–99.2) | 49.1 (44.5–55.0) | 36.0 (29.5–53.0) | 10.8 (9.6–12.3) | 86.1 (84.4–87.6) |
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Mean depth across target regions.
bMQ denotes mapping quality.
Note that the range of values is shown in the parenthesis.
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