Symbiotic Plant Peptides Eliminate Candida albicans Both In Vitro and in an Epithelial Infection Model and Inhibit the Proliferation of Immortalized Human Cells

Figure 4

Effects of the NCR peptides on PK E6/E7 vaginal epithelial cell—C. albicans coculture. The relative amount of viable, attached cells 40 hours after treatment was measured by RTCA as in Figure 3. 25 and 50 mg/L indicate treatments of the human cells only with peptides; C. albicans 25 μg/mL and C. albicans 50 μg/mL show the result from treatments of the cocultures with peptides at 25 μg/mL or 50 μg/mL concentrations, respectively. Significant () difference between the connected treatments. ^•The observed cell number significantly () differs from that of the mock (PBgluc) and infected (C. albicans) controls.