Cytotoxicity Studies of Novel Combretastatin and Pterostilbene Derivatives

Table 2

Growth inhibition effects of 1b–7b stilbenes on five cancer cell lines: breast cancer cells MDA-MB-231, pancreatic cancer cells PSN-1, colorectal cancer cells SW480, lung cancer cells A549 and ovarian cancer cells SKOV-3.

Stilbene	Cancer cells
	MDA-MB-231		PSN-1		SW480		A549		SKOV-3
	IC50/; 𝜇M	95% CI	IC50/; 𝜇M	95% CI	IC50/; 𝜇M	95% CI	IC50/; 𝜇M	95% CI	IC50/; 𝜇M	95% CI
1b	nonconverged	—	nonconverged	—	nonconverged	—	nonconverged	—	nonconverged	—
2b	nonconverged	—	156.5	111.5–219.8	260	220.5–306.5	nonconverged	—	nonconverged	—
3b	nonconverged	—	nonconverged	—	nonconverged	—	nonconverged	—	nonconverged	—
4b	nonconverged	—	nonconverged	—	nonconverged	—	nonconverged	—	nonconverged	—
5b	nonconverged	—	24.9	23.2–26.8	nonconverged	—	nonconverged	—	nonconverged	—
6b	nonconverged	—	104.4	57.3–190.0	nonconverged	—	nonconverged	—	nonconverged	—
7b	59.5	32.3–109.7	nonconverged	—	nonconverged	—	nonconverged	—	nonconverged	—