Attenuation of Collagen-Induced Arthritis in Rat by Nicotinic Alpha7 Receptor Partial Agonist GTS-21
Figure 4
Histological observation of joint inflammation cell and bone damage. Tissue sections were stained with HE to study inflammatory cell influx and bone destruction (original magnification ×100). (a) Control group treated with PBS; (b) group treated with GTS-21 concentration of 1 mg/kg; (c) the group treated by GTS-21 concentration of 2.5 mg/kg; (d) histological score analysis of these three groups. Date was determined according to the scale described in Section 2. * versus PBS control group. Data represent mean + standard errors of the mean and are representative of eight rats per group.
