Protective Effect of a Prime-Boost Strategy with the Ts87 Vaccine against Trichinella spiralis Infection in Mice
Protection elicited by immunization with different vaccination regimens. The larvae per gram muscle (LPG) were counted in the muscles of mice 6 weeks after a challenge with 400 T. spiralis larvae. The mice immunized with the DNA-prime/protein-boost (DNA + P) displayed a 46.1% reduction in the muscle larval burden compared to the groups immunized with the homologous DNA prime-boost (36.2%, ) and homologous protein prime-boost (24.6%, ). . . The results are presented as the mean ± SE for 6 mice per group.