Curcumin Loaded Microsponges for Colon Targeting in Inflammatory Bowel Disease: Fabrication, Optimization, and In Vitro and Pharmacodynamic Evaluation

Table 4

Macroscopic evaluation of colonic lesions of rat.

Colonic erosion score∗
Groups	0	0.5	1	1.5	2
Control	—	1	1	2	1
Curcumin	—	1	3	1	—
Curcumin microsponges	—	3	2	—	—

^∗𝑛=5 in each group; 0 = normal colored colon, 0.5 = red coloration, 1 = spot ulcer, 1.5 = hemorrhagic streaks, and 2 = hemorrhagic ulcer.