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BioMed Research International
Volume 2014, Article ID 341251, 8 pages
http://dx.doi.org/10.1155/2014/341251
Research Article

Influence of the Umbilical Cord Insertion Site on the Optimal Individual Birth Weight Achievement

1Gynaecology, Obstetric and Reproductive Medicine Department, Grenoble University Hospital, BP 217, 38043 Grenoble Cedex, France
2Commissariat à l’Energie Atomique (CEA), DSV-iRTSV, 38043 Grenoble Cedex, France
3Université Grenoble-Alpes, 38041 Grenoble, France
4Institut National de la Santé et de la Recherche Médicale U1036 (INSERM U1036), Laboratoire Biologie du Cancer et de l’Infection (BCI), Laboratoire BCI-iRTSV, CEA Grenoble, 17 rue des Martyrs, 38054 Grenoble Cedex 9, France
5UJF-Grenoble 1, CNRS, TIMC-IMAG UMR 5525, Themas, 38041 Grenoble, France

Received 8 February 2014; Revised 27 April 2014; Accepted 30 April 2014; Published 25 May 2014

Academic Editor: Andrew Horne

Copyright © 2014 Sophie Brouillet et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Study Question. To determine whether the umbilical cord insertion site of singleton pregnancies could be linked to the newborn birth weight at term and its individual growth potential achievement. Material and Methods. A cohort study including 528 records of term neonates was performed. Each neonate was assessed for growth adjusted for gestational age according to the infant’s growth potential using the AUDIPOG module. We considered two categories of umbilical cord insertions: central and peripheral. Intrauterine growth restriction was defined as birth weight below the 10th percentile. Statistical analysis was performed using Chi-square, Student’s t test, Wilcoxon test, ANOVA, and logistic regression. Results. We observed a total of 343 centrally inserted cords versus 185 peripheral cords. There were twice as many smokers in the mothers of the peripheral category compared to the centrally inserted ones. More importantly, we demonstrated that only 17/343 (5.0%) of infants with central cord insertion were growth restricted, compared to 37/185 (20.0%) of the infants born with a peripheral insertion. Neonates with centrally inserted cord were significantly heavier. Conclusion. The umbilical cord insertion site of singleton pregnancies is associated with the newborn’s birth weight at term and its individual growth potential achievement.