Simultaneous Changes of Spatial Memory and Spine Density after Intrahippocampal Administration of Fibrillar A<i>β</i><sub>1–42</sub> to the Rat Brain

<table>Golgi staining revealed changes in spine density after the fA<i>β </i><sub>1–42</sub>-injection (A). Apical dendritic spine density analysis showed that the amyloid treatment induced a decrease in spine density (<svg height="11.375" id="M24" style="vertical-align:-0.30096pt" version="1.1" viewbox="0 0 75.025002 11.375" width="75.025002" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>). In each experimental group 75 dendritic shafts of 3 animals were studied. The values represent the mean (±S.E.M.) (<svg height="11.125" id="M25" style="vertical-align:-0.17555pt" version="1.1" viewbox="0 0 36.237499 11.125" width="36.237499" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> rats per group).</table>

BioMed Research International

fig4

Figure 4

Figure 4: Simultaneous Changes of Spatial Memory and Spine Density after Intrahippocampal Administration of Fibrillar A<i>β</i><sub>1–42</sub> to the Rat Brain 

BioMed Research International

Simultaneous Changes of Spatial Memory and Spine Density after Intrahippocampal Administration of Fibrillar Aβ1–42 to the Rat Brain

Figure 4

Simultaneous Changes of Spatial Memory and Spine Density after Intrahippocampal Administration of Fibrillar Aβ_1–42 to the Rat Brain