MAVTgsa: An R Package for Gene Set (Enrichment) Analysis

Table 1

The original 𝑃 values and adjusted 𝑃 values (FDR and FWE) of the OLS and Hotelling’s 𝑇² test of P53 data.

GS name	GS size	OLS			𝑇^2
		𝑃 value	FDR	FWE	𝑃 value	FDR	FWE
hsp27Pathway	15	0*	0	0	0.0001*	0.0015	0.0003
p53hypoxiaPathway	20	0*	0	0	0*	0	0
p53Pathway	16	0*	0	0	0*	0	0
P53_UP	40	0*	0	0	0*	0	0
Radiation_sensitivity	26	0.0001*	0.0062	0.0741	0*	0	0
rasPathway	22	0.0015*	0.0770	0.3618	0.0989	0.2621	0.0576
HTERT_DOWN	64	0.0029*	0.1276	0.5490	0.0383	0.1636	0.1239
ST_Interleukin_4_Pathway	24	0.0079*	0.3042	0.2743	0.0039*	0.0375	0.1799
ck1Pathway	15	0.0089*	0.3046	0.3107	0.0068*	0.0582	0.1486
ngfPathway	19	0.0105	0.3102	0.2071	0.1313	0.2952	0.0862
inflamPathway	28	0.0133	0.3102	0.0737	0.0308	0.1492	0.0674
lairPathway	15	0.0134	0.3102	0.1119	0.0393	0.1636	0.2736
no2il12Pathway	17	0.0136	0.3102	0.2248	0.0245	0.1417	0.0549
cytokinePathway	21	0.0141	0.3102	0.2706	0.0290	0.1492	0.0217
badPathway	21	0.0157	0.3224	0.4702	0.0001*	0.0015	0

∗Denote 𝑃 values < 0.01.