Luminal DMSO: Effects on Detrusor and Urothelial/Lamina Propria Function

Table 1

Mean (±SEM) maximal responses (g) and pEC50 values for carbachol on tissue strips prepared from DMSO or control pretreated bladders.

Carbachol	Urothelium/lamina propria		Detrusor smooth muscle		Intact bladder strips
	Control	DMSO	Control	DMSO	Control	DMSO
Maximum response (g)	4.2±0.28	6.6±0.35^∗∗∗	17.8±1.4	17.1±0.7	8.3±0.63	11.5±0.94^∗
pEC50	4.14±0.09	4.4±0.08	4.37±0.12	4.39±0.07	4.35±0.14	4.45±0.52

^∗𝑃<0.05 and ^∗∗∗𝑃<0.001 when comparing control versus DMSO (50% v/v).