A Purified Recombinant Lipopeptide as Adjuvant for Cancer Immunotherapy
Figure 2
The responses of BM-DCs after stimulation with lipo-Nter. BM-DCs were generated from wild-type (WT), TLR1−/− (TLR1 KO), TLR2−/− (TLR2 KO), or TLR6−/− (TLR6 KO) mice. Different types of BM-DCs were stimulated with/without LPS (0.1 μg/mL) or lipo-Nter (100 nM) for 24 h. The levels of TNF- in the culture supernatant were measured by ELISA. LPS (TLR4 agonist) was used as positive control. The results are expressed as the means + S.D. of the amount of cytokine.
