Research Article
Helical Tomotherapy Combined with Capecitabine in the Preoperative Treatment of Locally Advanced Rectal Cancer
Table 2
Acute toxicities, perioperative complications, and late morbidities in patients with locally advanced rectal cancer.
| | Acute toxicities | (%) |
| | Grade 3 or 4 toxicities | 4 (11.1) | | Nausea/vomiting | | | Grade 1 | 5 (13.9) | | Grade 2 | 1 (2.8) | | Diarrhea | | | Grade 1 | 11 (30.6) | | Grade 2 | 10 (27.8) | | Grade 3 | 4 (11.1) | | Leukopenia | | | Grade 1 | 2 (5.6) | | Grade 2 | 1 (2.8) | | Anemia | | | Grade 2 | 3 (8.3) | | Frequency/urgency/cystitis | | | Grade 1 | 6 (16.7) | | Grade 2 | 3 (8.3) | | Dermatitis | | | Grade 1 | 22 (61.1) | | Grade 2 | 5 (13.9) | | Hand-foot syndrome | | | Grade 1 | 1 (2.8) | | Grade 2 | 1 (2.8) |
| | Perioperative complications | (%) |
| | Anastomotic leakage (after low anterior resection) | 2 (6.9) | | Pelvic abscess (after low anterior resection) | 1 (3.4) |
| | Late morbidities | (%) |
| | Grade ≥ 3 toxicities | 5 (14.3) | | Colitis | | | Grade 1 | 3 (8.6) | | Grade 2 | 2 (5.7) | | Small bowel obstruction | | | Grade 2 | 2 (5.7) | | Grade 3 | 2 (5.7) | | Anastomotic stenosis | | | Grade 1 | 1 (2.9) | | Grade 2 | 4 (11.4) | | Grade 3 | 1 (2.9) | | Fistula | | | Grade 4 | 2 (5.7) | | Chronic diarrhea | | | Grade 1 | 4 (11.4) | | Grade 2 | 2 (5.7) | | Stool incontinence | | | Grade 2 | 1 (2.9) | | Ureter adhesion or stricture | | | Grade 1 | 4 (11.4) | | Grade 2 | 3 (8.6) | | Cystitis and/or hematuria | | | Grade 1 | 4 (11.4) | | Grade 2 | 4 (11.4) |
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