Rapid Purification of a New P-I Class Metalloproteinase from Bothrops moojeni Venom with Antiplatelet Activity

Figure 6

Light micrographs of section of mouse kidney 24 hours after i.p. injection of B. moojeni crude venom or BmooMPα-II (50 μg/100 μL saline), stained with hematoxylin-eosin. (a) Control: normal cortical region in the kidney. (b-c) and (d-e) B. moojeni crude venom and BmooMPα-II, respectively: note renal tubular degeneration with cell debris formation and inflammatory infiltrate. Letters indicate the presence of renal tubular degeneration (D) and inflammatory infiltrate (I). Scale bar = 100 μm (a, b, d); scale bar = 50 μm (c, e).

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