Inhibition of Nitric Oxide Synthase Prevents Muscarinic and Purinergic Functional Changes and Development of Cyclophosphamide-Induced Cystitis in the Rat

Table 2

Receptor expression and mast cell occurrence as judged by muscarinic M5 receptor-like, P1A1 purinoceptor-like and MIF-like staining in the detrusor muscle in saline and CYP-treated rats that had received saline, 4-DAMP, or L-NAME pretreatment (𝑛=5 in each group). 0, (+), +, ++ refer to none (or almost none), possibly occurring, occurring, and obvious, respectively.

	Muscarinic M5 receptor-like staining	P1A1 purinoceptor-like staining	MIF-like staining
Saline-saline	+	+	(+)
Saline-CYP	++	(+)	++
4-DAMP-saline	+	+	(+)
4-DAMP-CYP	++	(+)	++
L-NAME-saline	+	+	(+)
L-NAME-CYP	(+)	+/(+)	+