Nodal Promotes the Self-Renewal of Human Colon Cancer Stem Cells via an Autocrine Manner through Smad2/3 Signaling Pathway
Figure 1
mRNA expression of Nodal ligand and its three receptors in various human colorectal cancer cell lines. (a–c) RT-PCR revealed the transcripts of Nodal, ALK-4, ALK-7, and Actr-IIb in human colon cancer cell lines, including SW480 cells (a), LOVO cells (b), and HCT116 cells (c). Gapdh served as a loading control of total RNA.
