Deregulation of Serum MicroRNA Expression Is Associated with Cigarette Smoking and Lung Cancer

Figure 1

Heat map of the hierarchical clustering of 448 differentially expressed miRNAs in nonsmoker controls (C), smokers (S), and lung-cancer patients (T). (a) T versus C; (b) S versus C; (c) S versus T. Clustering is significant, with a value of 0.001, according to Fisher’s test. The miRNAs are shown on the -axis and the groups are shown on the -axis. Red indicates high expression and green indicates low expression of miRNAs.

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