Long-Term Outcomes after Dialysis-Requiring Acute Kidney Injury

Table 3

Risk of long-term mortality stratified by dialysis status after index hospital discharge by Cox proportional hazard model with time-varying covariates.

	HR	Lower 95% CI	Upper 95% CI
Age (per year)	1.04	1.04	1.05	<0.001
Charlson score	1.17	1.13	1.20	<0.001
Male	1.28	1.17	1.40	<0.001
Groups
Nonwithdrawal versus dialysis withdrawal subgroup	1.63	1.39	1.91	<0.001
Non-AKI versus dialysis withdrawal subgroup	0.65	0.43	0.83	<0.001
Dementia	1.34	1.07	1.69	0.012
Severe liver disease	1.88	1.39	2.56	0.012
During index hospitalization
Respiratory failure during index hospitalization	1.24	1.05	1.47	<0.001
Lower GI surgery	1.63	1.15	2.29	0.005
ICU admission during index hospitalization	1.22	1.09	1.37	<0.001
Use of diuretics 2.25 DDD at dialysis initiation	1.15	1.03	1.28	0.011
Statin use after discharge	0.77	0.65	0.92	0.003
Diuretics use after discharge	1.28	1.15	1.41	<0.001
Time-varying ESRD event	1.70	1.47	1.98	<0.001

Adjusted generalized ; concordance index = 0.83.
AKI, acute kidney injury; CI, confidence interval; DDD, defined daily dose; ESRD, end-stage renal disease; GI, gastrointestinal; HR, hazard ratio.