Research Article
Molecular Profiling and Clinical Outcome of High-Grade Serous Ovarian Cancer Presenting with Low- versus High-Volume Ascites
Table 1
Gene ontology (GO) categories enriched in the low-volume ascites group.
| GO term | GO accession | value | Corrected value |
| Antigen processing and presentation | GO:0019882/GO:0030333 | | | Antigen processing and presentation of endogenous antigen | GO:0019883 | | 0.1561 | Antigen processing and presentation of peptide or polysaccharide antigen via MHC class II | GO:0002504 | | | Chemokine activity | GO:0008009 | | 0.0032 | Chemokine receptor binding | GO:0042379 | | 0.0041 | Chemotaxis | GO:0006935 | | 0.0362 | Cytokine activity | GO:0005125 | | 0.0010 | Cytokine receptor binding | GO:0005126 | | 0.0549 | Defense response | GO:0006952/GO:0002217/GO:0042829 | | | Extracellular region | GO:0005576 | | 0.1764 | Extracellular region part | GO:0044421 | | 0.0362 | Extracellular space | GO:0005615 | | 0.0032 | Fatty acid biosynthetic process | GO:0006633/GO:0000037 | | 0.0890 | G-protein-coupled receptor binding | GO:0001664 | | 0.0020 | Icosanoid biosynthetic process | GO:0046456 | | 0.0971 | Immune response | GO:0006955 | | | Immune system process | GO:0002376 | | | Inflammatory response | GO:0006954 | | 0.0129 | Locomotion | GO:0040011 | | 0.1595 | Membrane | GO:0016020 | | 0.0890 | Membrane raft | GO:0045121 | | 0.0535 | MHC class II protein complex | GO:0042613 | | | MHC class II receptor activity | GO:0032395 | | | MHC protein complex | GO:0042611 | | | Multiorganism process | GO:0051704/GO:0051706 | | 0.0583 | Oligopeptide transport | GO:0006857 | | 0.1561 | Oligopeptide transporter activity | GO:0015198 | | 0.1561 | Phospholipid efflux | GO:0033700 | | 0.1858 | Polyamine biosynthetic process | GO:0006596 | | 0.1273 | Protein binding | GO:0005515/GO:0045308 | | 0.1065 | Receptor binding | GO:0005102 | | 0.0094 | Response to biotic stimulus | GO:0009607 | | 0.0271 | Response to other organisms | GO:0051707/GO:0009613/GO:0042828 | | 0.0041 | Response to stimulus | GO:0050896/GO:0051869 | | 0.0089 | Response to stress | GO:0006950 | | 0.0414 | Response to virus | GO:0009615 | | 0.0381 | Response to wounding | GO:0009611/GO:0002245 | | 0.1065 | Taxis | GO:0042330 | | 0.0362 | Unsaturated fatty acid biosynthetic process | GO:0006636 | | 0.1138 | Vacuolar membrane | GO:0005774 | | 0.1065 | Vacuolar part | GO:0044437 | | 0.1179 | Vacuole | GO:0005773 | | 0.1065 |
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