Effect of Dietary 𝑛−3 Polyunsaturated Fatty Acids on Oxidant/Antioxidant Status in Macrosomic Offspring of Diabetic Rats

Table 3

VLDL-LDL-fatty acid compositions from control and obese offspring.

	Day 0	Day 0	Day 90	Day 90
	Control	Macrosomic	Control	Macrosomic
SFA
ISIO	35.08 ± 1.54	42.11 ± 2.64∗∗	37.20 ± 2.48	39.97 ± 2.91
EPAX	35.3 ± 2.97	35.05±1.11^§	34.95 ± 3.59	37 ± 2.34
MUFA
ISIO	24.95 ± 2.14	21.67 ± 2.25	19.61 ± 1.86	18.52 ± 2.75
EPAX	23.06 ± 1.97	22.56 ± 2.39	20.31 ± 2.34	19.31 ± 1.76
18:2 (𝑛−6)
ISIO	13.25 ± 2.65	6.18 ± 0.86∗∗	18.72 ± 2.01	6.53 ± 1.63∗∗
EPAX	10.07 ± 1.24	9.6 ± 0.78	15.82 ± 1.83	10.19±1.73^§§
20:4 (𝑛−6)
ISIO	21.25 ± 1.09	26.63 ± 1.17∗∗	20.17 ± 1.97	10.75 ± 0.89∗∗
EPAX	18.26±1.01^§	17.85±1.24^§§	12.84±1.10^§§	11.34 ± 0.78
EPA 20:5 (𝑛−3)
ISIO	1.07 ± 0.48	1.51 ± 0.24	1.18 ± 0.24	1.26 ± 0.33
EPAX	5.63±0.62^§§	5.66±0.85^§§	8.05±1.01^§§	7.84±1.01^§§
DHA 22:6 (𝑛−3)
ISIO	1.26 ± 0.74	0.58 ± 0.24∗	1.97 ± 0.26	1.62 ± 0.27
EPAX	6.09±0.82^§§	7.35±0.38^§§	5.85±0.62^§§	7.27±0.83^§§

Values are expressed as a percentage of the total fatty acids and are mean ± SD; 𝑛=8 rats. Day 0: birth; day 90: adulthood; DHA: docosahexaenoic acid; EPA: eicosapentaenoic acid; EPAX: EPAX diet; ISIO: ISIO diet; MUFA: monounsaturated fatty acids; SFA: saturated fatty acids. Data were analysed statistically by ANOVA. Significant differences between macrosomic and control rats and between Isio-4 and EPAX diets at each age were assessed using Student’s 𝑡 test. ^∗𝑃<0.05 and  ^∗∗𝑃<0.01 compared with the control group. ^§𝑃<0.05 and ^§§𝑃<0.01 compared with the group fed with the ISIO diet.