Nerve Regenerative Effects of GABA-B Ligands in a Model of Neuropathic Pain

Figure 7

Neuroimmune response in peripheral nerves is modulated by GABA-B ligands. Immunofluorescence images of coronal sections of sciatic nerves of sham and PSL rats treated with baclofen 10 mg/kg, CGP56433 3 mg/kg, and baclofen plus CGP56433. Myelin structures are evidenced in red with Fluoromyelin. Macrophages specific marker CD68 is in green. Nuclei are stained in blue with DAPI. Scale bar 20 μm.