Research Article

Alcohol Induced Mitochondrial Oxidative Stress and Alveolar Macrophage Dysfunction

Figure 5

EtOH exposure induced mitochondrial fragmentation, condensation, and perinuclear clustering. Mitochondrial morphology analysis was monitored using mitoTracker green. Representative confocal microscopic images for untreated (none) and EtOH treated (0.2%, 5d) MH-S cells are shown in (a). The value of form factor (FF) and aspect ratio (AR) was plotted for each treatment condition ( ). For identification of mitochondria, mAMs from control or EtOH-fed mice were loaded with mitoTracker green (representative confocal microscopic images in (b)).
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(a)
371593.fig.005b
(b)