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BioMed Research International
Volume 2014, Article ID 379340, 11 pages
http://dx.doi.org/10.1155/2014/379340
Research Article

Lentiviral Protein Transduction with Genome-Modifying HIV-1 Integrase-I-PpoI Fusion Proteins: Studies on Specificity and Cytotoxicity

1Department of Biotechnology and Molecular Medicine, A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, 70210 Kuopio, Finland
2FinVector Vision Therapies Oy, 70210 Kuopio, Finland
3FKD Therapies Oy, 70210 Kuopio, Finland
4Department of Medicine, University of Eastern Finland, 70120 Kuopio, Finland
5Gene Therapy Unit, Kuopio University Hospital, 70120 Kuopio, Finland

Received 26 January 2014; Accepted 12 March 2014; Published 22 April 2014

Academic Editor: Brian Oliver

Copyright © 2014 Vesa Turkki et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [5 citations]

The following is the list of published articles that have cited the current article.

  • Annukka M Kivelä, Jenni Huusko, and Seppo Ylä-Herttuala, “Prospect and progress of gene therapy in treating atherosclerosis,” Expert Opinion on Biological Therapy, pp. 1–14, 2015. View at Publisher · View at Google Scholar
  • Kristian Alsbjerg Skipper, and Jacob Giehm Mikkelsen, “Delivering the Goods for Genome Engineering and Editing,” Human Gene Therapy, vol. 26, no. 8, pp. 486–497, 2015. View at Publisher · View at Google Scholar
  • Yujia Cai, and Jacob Giehm Mikkelsen, “Lentiviral delivery of proteins for genome engineering,” Current Gene Therapy, vol. 16, no. 3, pp. 194–206, 2016. View at Publisher · View at Google Scholar
  • Kristian Alsbjerg Skipper, Mathias Gaarde Nielsen, Sofie Andersen, Laura Barrett Ryø, Rasmus O. Bak, and Jacob Giehm Mikkelsen, “Time-Restricted PiggyBac DNA Transposition by Transposase Protein Delivery Using Lentivirus-Derived Nanoparticles,” Molecular Therapy - Nucleic Acids, vol. 11, pp. 253–262, 2018. View at Publisher · View at Google Scholar
  • Jacob Giehm Mikkelsen, “Viral delivery of genome-modifying proteins for cellular reprogramming,” Current Opinion in Genetics & Development, vol. 52, pp. 92–99, 2018. View at Publisher · View at Google Scholar