Macrophage Capping Protein CapG Is a Putative Oncogene Involved in Migration and Invasiveness in Ovarian Carcinoma
Figure 1
CapG expression in normal and OC tumor tissues. CapG expression in primary tumor tissue samples from 47 patients with OC was analyzed by qRT-PCR and compared to normal adjacent tissue samples (). Single probes were normalized to housekeeping gene GAPDH. Mean expression in normal tissue was calculated and standard deviation added for upper cutoff (dashed line). Thus, expression levels greater than 2.0-fold above mean CapG expression in controls was defined as overexpression and 38% of all tumor samples display such results. To the right, CapG expression of ovarian carcinoma cell lines OvCa-3, SK-OV-3, MDAH, and Hey. Each sample was analyzed in duplicates and repeated three times.
