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BioMed Research International
Volume 2014, Article ID 383859, 5 pages
Research Article

Detection of Toxoplasma gondii by PCR and Mouse Bioassay in Rodents of Ahvaz District, Southwestern Iran

1Department of Medical Parasitology, Ahvaz Jundishapur University of Medical Sciences, Ahvaz 613715794, Iran
2Health Research Institute, Infectious and Tropical Diseases Research Center, Ahvaz Jundishapur University of Medical Science, Ahvaz, Iran
3Research Institute for Infectious Diseases of Digestive System, Ahvaz Jundishapur University of Medical Sciences, Ahvaz 613715794, Iran

Received 4 April 2013; Revised 22 October 2013; Accepted 6 November 2013; Published 29 January 2014

Academic Editor: Jacques Cabaret

Copyright © 2014 J. Saki and S. Khademvatan. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Toxoplasma gondii is obligate coccidian zoonotic parasite. Felidae family is definitive and wide ranges of warm-blooded vertebrates are intermediate hosts for the parasite. Rodents are measured as an important source of T. gondii infection for the definitive host. Thus, this study aimed to investigate Toxoplasm infection in rodents of Ahvaz district, southwest of Iran. A total of 100 rodents (73 Rattus norvegicus, 21 Rattus rattus, and 6 Mus musculus) were collected and studied by GRA6PCR and mouse bioassay. The finding indicated that 6 out of 100 (6%) and 2 out of 100 (2%) samples were positive by PCR and mouse bioassay, respectively. The results show notable chronic infection in the rodent and potential transmission of the infection among animal and men in the region. Accordingly, this study recommended investigating of the T. gondii infection in definitive and other intermediate hosts in other points of Khuzestan province, Southwest, Iran.