Research Article

Synergistic Effect of MiR-146a Mimic and Cetuximab on Hepatocellular Carcinoma Cells

Figure 11

miR-146a mimic increased the caspase-3/7 activity of cetuximab in HCC HepG2 cells. HepG2 cells (2.5 × 103 cells per well in 96-well plate) were cultured for 24 h then transfected with miR-146a mimic and negative control (200 nM). Meanwhile, cetuximab was added and the cells were cultured up to another 96 h. Caspase activity was performed as above. , compared to agent alone of the same concentration.
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