Research Article

Establishment of a Swine Model for Validation of Perfusion Measurement by Dynamic Contrast-Enhanced Magnetic Resonance Imaging

Figure 6

Signal curves of arterial input functions (AIF) of the aorta. The figure shows curves of three measurements after administration of the BPCM. The curves of the second and third measurements have a higher baseline signal than the first curve because of persisting effects of CM administered for the preceding measurement (a). Relaxation rate change versus time of the arterial blood measured in the aorta. The relaxation rate change curves were calculated with the method of Li et al. using the same data as for (a). The CM preload has no evident effect on the curves (b). Signal tissue curves of semitendinosus muscle using LMCM. As far as possible, no bones, skin, or great vessels were included (c). Corresponding to the method used in (c), relaxation rate change versus time curves were generated (d). Relaxation rate change versus time of the AIF of a 17-year-old female sarcoma patient measured in a vessel in the lower extremity using a BPCM (e). Relaxation rate change versus time of a tissue curve measured in a muscle of the lower extremity of the sarcoma patient using an LMCM (f).
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(a)
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(b)
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(c)
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(d)
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(e)
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(f)