Research Article
Outcome and Prognostic Factors in T4a Oropharyngeal Carcinoma, Including the Role of HPV Infection
Table 1
Oncologic results according to treatment group.
| Treatment group | Number of patients | 5-Y-KM-Estimate (%) (total number of events) (95% CI) | OS | DSS | LC | RC | DC |
| Primary surgical group | 83 | 41.2 (67) (30–52) | 52.7 (35) (41–65) | 74.2 (16) (63–86) |
*
84.7 (8) (75–95) |
*
86.5 (6) (76–97) | Surgery | 19 | 30.4 (16) (6–54) |
*47.2 (8) (19–75) |
*55.6 (5) (26–85) |
*67.5 (2) (27–100) | No events* | Surgery + RT | 38 | 38.9 (33) (21–52) | 41.8 (20) (25–58) |
*75.7 (8) (6–91) |
*81.6 (5) (67–96) |
*90.0 (2) (76–100) | Surgery + RCT | 26 | 56.7 (18) (37–76) |
*72.7 (7) (54–92) |
*87.5 (3) (71–100) |
*95.8 (1) (87–100) | 56.7 (18) (37–76) | Primary conservative group | 316 | 17.3 (263) (13–22) | 31.4 (184) (23–39) | 83.8 (43) (79–89) | 91.8 (11) (86–97) | 80.4 (20) (71–89) | RCT ± salvage | 151 | 18.6 (129) (12–25) | 33.8 (91) (24–42) | 83.5 (21) (76–91) |
*96.0 (4) (92–100) | 76.8 (11) (62–91) | RT ± salvage | 165 | 16.8 (134) (11–23) | 29.6 (93) (21–38) | 84.2 (22) (78–91) |
*88.8 (7) (80–98) | 83.0 (9) (71–95) |
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Not enough events or patients for statistical analysis.
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