Rho GTPase-Activating Protein 35 rs1052667 Polymorphism and Osteosarcoma Risk and Prognosis

Table 2

The rs1052667 polymorphism of ARHGAP35 and osteosarcoma risk.

rs1052667	Controls		Cases		OR	𝑃
	𝑛	%	𝑛	%
Genotype
CC	341	79.7	133	53.8	1
CT	72	16.8	70	28.3	2.41 (1.64–3.55)^a	9.00×10^−6
TT	15	3.5	44	17.8	7.35 (3.95–13.68)^a	3.12×10^−10
CT/TT^b	87	20.3	114	46.2	3.27 (2.31–4.61)^a	1.92×10^−11
Allele
C	754	88.1	336	68.0	1
T	102	11.9	158	32.0	2.25 (1.64–3.09)	4.43×10^−7

aOR conditional on matched set adjusted by smoking and drinking status, radiation exposure history, trauma history, paget’s disease history, and benign bone lesions.
^bCT/TT represented the combination of rs1052667-CT genotype and rs1052667-TT genotype.