Study of the Association between ITPKC Genetic Polymorphisms and Calcium Nephrolithiasis
Figure 2
Effects of ITPKC on calcium influx in HEK293 cells. Thapsigargin (TG; 2 μM) was applied in a Ca2+-free BSS solution. The extracellular Ca2+ concentration abruptly increased from 0 to 2 mM which triggered the store-operated (SOC) channel influx.
