Detecting Epistatic Interactions in Metagenome-Wide Association Studies by metaBOOST

Table 1

Top 10 candidate genus epistatic interactions in the type II diabetes dataset.

Genus A	Genus B	P value	q-value
Bifidobacterium	Actinobacillus	0	0
Aggregatibacter	Arcanobacterium	6𝑒−6	0.084
Pyramidobacter	Proteus	8𝑒−6	0.084
Acidaminococcus	Ureaplasma	2𝑒−5	0.119
Rhizobium	Veillonella	2.3𝑒−5	0.119
Micrococcus	Scardovia	2.4𝑒−5	0.119
Megamonas	Selenomonas	2.8𝑒−5	0.119
Burkholderiales	Abiotrophia	3𝑒−5	0.119
Kingella	Desulfotomaculum	3.5𝑒−5	0.123
Catenibacterium	Aliivibrio	4.2𝑒−5	0.133