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BioMed Research International
Volume 2014, Article ID 398190, 9 pages
Research Article

Combined Home Exercise Is More Effective Than Range-of-Motion Home Exercise in Patients with Ankylosing Spondylitis: A Randomized Controlled Trial

1Department of Physical Medicine and Rehabilitation, Shin Kong Wu Ho-Su Memorial Hospital, Taipei 11101, Taiwan
2School of Medicine, Fu Jen Catholic University, New Taipei City 24205, Taiwan
3Department of Allergy, Immunology and Rheumatology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei 11101, Taiwan
4Division of Allergy, Immunology and Rheumatology, Chung Shan Medical University Hospital, Taichung City 40201, Taiwan
5Institute of Medicine, Chung Shan Medical University, Taichung City 40201, Taiwan
6Graduate Institute of Integrated Medicine, China Medical University, No. 110, Sec. 1, Jianguo N. Road, South District, Taichung City 40201, Taiwan
7Graduate Institute of Biomedical Engineering, National Taiwan University of Science and Technology, Taipei 10607, Taiwan
8National Defense Medical Center, Taipei 11490, Taiwan
9University of Taipei, Taipei 11153, Taiwan

Received 30 May 2014; Revised 8 August 2014; Accepted 17 August 2014; Published 7 September 2014

Academic Editor: Hsi-Kai Tsou

Copyright © 2014 Lin-Fen Hsieh et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Home exercise is often recommended for management of patients with ankylosing spondylitis (AS); however, what kind of home exercise is more beneficial for patients with AS has not been determined yet. We aimed to compare the effectiveness of combined home exercise (COMB) and range-of-motion home exercise (ROM) in patients with AS. Nineteen subjects with AS completed either COMB () or ROM () program. The COMB program included range-of-motion, strengthening, and aerobic exercise while the ROM program consisted of daily range-of-motion exercise only. After exercise instruction, subjects in each group performed home exercise for 3 months. Assessment included cardiopulmonary exercise test, pulmonary function test, spinal mobility measurement, chest expansion, Bath Ankylosing Spondylitis Functional Index (BASFI), and other functional ability and laboratory tests. After exercise, the COMB group showed significant improvement in peak oxygen uptake (12.3%, ) and BASFI (), and the changed score between pre- and postexercise data was significantly greater in the COMB group regarding peak oxygen uptake and BASFI. Significant improvement in finger-to-floor distance after 3-month exercise was found only in the COMB group (). This study demonstrates that a combined home exercise is more effective than range-of-motion home exercise alone in aerobic capacity and functional ability.