Table of Contents Author Guidelines Submit a Manuscript
BioMed Research International
Volume 2014, Article ID 401213, 12 pages
http://dx.doi.org/10.1155/2014/401213
Review Article

Holoptelea integrifolia (Roxb.) Planch: A Review of Its Ethnobotany, Pharmacology, and Phytochemistry

Department of Botany, Maharshi Dayanand University, Rohtak, Haryana, India

Received 14 February 2014; Accepted 9 April 2014; Published 18 May 2014

Academic Editor: Ziad Daoud

Copyright © 2014 Showkat Ahmad Ganie and Surender Singh Yadav. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. S. H. Samsam and F. Moatar, Natural Medicines and Plants, Mashal Publications, Tehran, Iran, 1991.
  2. R. P. Borris, “Natural products research: perspectives from a major pharmaceutical company,” Journal of Ethnopharmacology, vol. 51, no. 1–3, pp. 29–38, 1996. View at Publisher · View at Google Scholar · View at Scopus
  3. A. Singh, “Exotic floristic diversity of the Varanasi district of Uttar Pradesh, India,” Indian Journal of Plant Sciences, vol. 1, pp. 73–84, 2012. View at Google Scholar
  4. V. D. Bambhole and G. G. Jiddewar, “Antiobesity effect of Iris versicolor and Holoptelea integrifolia in rats,” Sachitra Ayurveda, vol. 37, pp. 557–561, 1985. View at Google Scholar
  5. P. K. Warrier, V. P. K. Nambiar, and C. Ramakutty, Indian Medicinal Plants: A Compendium of 500 Species, Orient Longman, 1995.
  6. N. D. Prajapati, S. S. Purohit, and A. K. Sharma, A Handbook of Medicinal Plants: A Complete Source Book, Agrobias, Jodhpur, India, 2003.
  7. K. M. Nandkani, Indian Materia Medica, Popular Prakashan, Mumbai, India, 1976.
  8. J. K. P. Benjamin and P. K. S. Christopher, “Preliminary phytochemical and pharmacognostic studies of Holoptelea integrifolia Roxb,” Ethnobotanical Leaflets, vol. 13, pp. 1222–1231, 2009. View at Google Scholar
  9. V. K. Singh and Z. A. Ali, “Folk medicines in primary health care: common plants used for the treatment of fevers in India,” Fitoterapia, vol. 65, no. 1, pp. 68–74, 1994. View at Google Scholar · View at Scopus
  10. V. H. Harsha, S. S. Hebbar, V. Shripathi, and G. R. Hegde, “Ethnomedicobotany of Uttara Kannada district in Karnataka, India plants in treatment of skin diseases,” Journal of Ethnopharmacology, vol. 84, no. 1, pp. 37–40, 2003. View at Publisher · View at Google Scholar · View at Scopus
  11. P. Mahishi, B. H. Srinivasa, and M. B. Shivanna, “Medicinal plant wealth of local communities in some villages in Shimoga district of Karnataka, India,” Journal of Ethnopharmacology, vol. 98, no. 3, pp. 307–312, 2005. View at Publisher · View at Google Scholar · View at Scopus
  12. J. G. Graham, M. L. Quinn, D. S. Fabricant, and N. R. Farnsworth, “Plants used against cancer—an extension of the work of Jonathan Hartwell,” Journal of Ethnopharmacology, vol. 73, no. 3, pp. 347–377, 2000. View at Publisher · View at Google Scholar · View at Scopus
  13. M. Parinitham, G. U. Harish, N. C. Vivek, T. Mahesh, and M. B. Shivanna, “Ethnobotanical wealth of Bhadra wild life sanctuary in Karnataka,” Indian Journal of Traditional Knowledge, vol. 3, pp. 37–50, 2004. View at Google Scholar
  14. N. Rajakumar and M. B. Shivanna, “Ethno-medicinal application of plants in the eastern region of Shimoga district, Karnataka, India,” Journal of Ethnopharmacology, vol. 126, no. 1, pp. 64–73, 2009. View at Publisher · View at Google Scholar · View at Scopus
  15. C. P. Khare, Indian Medicinal Plants: An Illustrated Dictionary, Spinger Science, 2007.
  16. N. V. Vinod, M. Haridas, and C. Sadasivan, “Isolation of 1,4-naphthalenedione, an antibacterial principle from the leaves of Holoptelea integrifolia and its activity against β-lactam resistant Staphylococcus aureus,” Indian Journal of Biochemistry and Biophysics, vol. 47, no. 1, pp. 53–55, 2010. View at Google Scholar · View at Scopus
  17. P. Padmaa and N. Durga, “Antibacterial activity of different extracts of stem bark of Holoptelea integrifolia,” International Research Journal of Pharmacy, vol. 2, pp. 111–113, 2011. View at Google Scholar
  18. S. Ahmad, R. Sharma, S. Mahajan, R. Agnihotri, and A. Gupta, “Antibacterial evaluation and preliminary phytochemical analysis of the leaf extract of Holoptelea integrifolia,” Journal of Pharmacy Research, vol. 5, pp. 3823–3825, 2012. View at Google Scholar
  19. S. D. Joshi, C. S. Hallikeri, and V. H. Kulkarni, “Evaluation of antibacterial and antitubercular activities of Holoptelea integrifolia (Roxb) Planch bark,” Universal Journal of Pharmacy, vol. 02, pp. 87–90, 2013. View at Google Scholar
  20. B. S. Reddy, R. K. K. Reddy, V. G. M. Naidu et al., “Evaluation of antimicrobial, antioxidant and wound-healing potentials of Holoptelea integrifolia,” Journal of Ethnopharmacology, vol. 115, no. 2, pp. 249–256, 2008. View at Publisher · View at Google Scholar · View at Scopus
  21. K. K. Sahoo, V. K. Yadav, and A. R. Saxena, “Antifungal properties of Holoptelea integrifolia (Roxb.) Planch,” Annals of Plant Protection Sciences, vol. 18, pp. 438–442, 2010. View at Google Scholar
  22. K. B. Ishnava, K. H. Chauhan, and C. A. Bhatt, “Screening of antifungal activity of various plant leaves extracts from Indian plants,” Archives of Phytopathology and Plant Protection, vol. 45, no. 2, pp. 152–160, 2012. View at Publisher · View at Google Scholar · View at Scopus
  23. S. Sharma, K. Lakshmi, A. Patidar, A. Chaudhary, and S. Dhaker, “Studies on anti-inflammatory effect of aqueous extract of leaves of Holoptelea integrifolia, Planch. in rats,” Indian Journal of Pharmacology, vol. 41, no. 2, pp. 87–88, 2009. View at Publisher · View at Google Scholar · View at Scopus
  24. Kalpana and A. Upadhyay, “Anti-inflammatory evaluation of ethanolic extract of leaves of Holoptelea integrifolia Planch,” Scholars Research Library, vol. 1, no. 2, pp. 185–195, 2010. View at Google Scholar
  25. D. Nadella and P. M. Paarakh, “Evaluation of anthelmintic activity of Holoptelea integrifolia (Roxb.) Planch,” International Journal of Research in Ayurveda and Pharmacy, vol. 1, pp. 637–641, 2011. View at Google Scholar
  26. S. Kaur, B. Kumar, S. Puri, P. Tiwari, and K. Divakar, “Comparative study of anthelmintic activity of aqueous and ethanolic extract of bark of Holoptelea integrifolia,” International Journal of Drug Development and Research, vol. 2, no. 4, pp. 758–763, 2010. View at Google Scholar · View at Scopus
  27. A. Saraswathy, D. S. Nandini, and D. Ramasamy, “Antioxidant, heavy metals and elemental analysis of Holoptelea integrifolia Planch,” Indian Journal of Pharmaceutical Sciences, vol. 70, no. 5, pp. 683–686, 2008. View at Publisher · View at Google Scholar · View at Scopus
  28. J. Srivastava, K. N. Dwivedi, and H. P. Pandey, “Assessment of antioxidant activity and total phenolic content of aqueous stem bark extract of Holoptelea integrifolia Planch,” International Journal of Pharmacy and Pharmaceutical Sciences, vol. 5, pp. 357–361, 2013. View at Google Scholar
  29. M. K. Mamatha, Phytochemical investigation and antidiabetic activity of Holoptelea integrifolia Planch [M.S. thesis], KLE University, Karnataka, India, 2009.
  30. S. Sharma, P. Khatri, A. Pandey, V. Jakhetia, L. Chaturvedi, and N. Dwivedi, “Anti-diabetic screening of leaves extract of Holoptelea integrifolia Roxb,” International Journal of Pharmaceutical Research and Development, vol. 2, pp. 66–71, 2010. View at Google Scholar
  31. J. Sharma, S. C. Sharma, Y. S. Sarangdevot, and B. Vyas, “Study of antidiabetic activity of the stem bark extract of Holoptelea integrifolia (Roxb.),” Research Journal of Pharmacology and Pharmacodynamics, vol. 4, pp. 181–184, 2012. View at Google Scholar
  32. S. Shrinivas, K. S. Lakshmi, and T. Rajesh, “Evaluation of antidiarrhoeal potentials of ethanolic extract of leaves of Holoptelea integrifolia in mice model,” International Journal of Pharmaceutical Research, vol. 1, no. 3, pp. 832–836, 2009. View at Google Scholar · View at Scopus
  33. A. Panossian, G. Wikman, and H. Wagner, “Plant adaptogens III. Earlier and more recent aspects and concepts on their mode of action,” Phytomedicine, vol. 6, no. 4, pp. 287–300, 1999. View at Google Scholar · View at Scopus
  34. B. Kumar, S. Puri, J. Debnath, M. Salhan, M. kaur, and A. Mittal, “Comparative pharmacological evaluation of adaptogenic activity of Holoptelea integrifolia and Withania somnifera,” International Journal of Drug Development and Research, vol. 3, no. 1, pp. 84–98, 2011. View at Google Scholar · View at Scopus
  35. K. S. Lakshmi, S. S. Sharma, T. Rajesh, and V. Chitra, “Antitumour activity of ethanolic extract of leaves of Holoptelea integrifolia on Dalton′s ascitic lymphoma in Swiss albino mice,” International Journal of Green Pharmacy, vol. 4, no. 1, pp. 44–47, 2010. View at Publisher · View at Google Scholar · View at Scopus
  36. J. Soujanya, P. Silambujanaki, and V. Leela Krishna, “Anticancer efficacy of Holoptelea integrifolia, Planch. against 7, 12-dimethyl benz(a)anthracene induced breast carcinoma in experimental rats,” International Journal of Pharmacy and Pharmaceutical Sciences, vol. 3, no. 5, pp. 103–106, 2011. View at Google Scholar · View at Scopus
  37. H. Guo, D. S. Wang, G. H. Rizwani et al., “Antineoplastic activity of Holoptelea integrifolia (Roxb.) Planch bark extracts (in vitro),” Pakistan Journal of Pharmaceutical Sciences, vol. 26, pp. 1151–1156, 2013. View at Google Scholar
  38. S. C. Ramzi, K. Vinay, and R. Stanley, Pathologic Basis of Diseases, WB Saunders, Philadelphia, Pa, USA, 1994.
  39. K. K. Khanna, V. Mudgal, G. Shukla, and P. K. Shrivastav, “Unreported ethnomedicinal uses of plants from Mirazapur district, Uttar Pradesh,” in Ethnobotany in South Asia, J. K. Mahalakshmi, Ed., Scientific Publishers, Jodhpur, India, 1996. View at Google Scholar
  40. K. K. Singh and A. Prakash, “Observation on ethnobotany of Kol tribe of Varanasi district, Uttar Pradesh,” in Ethnobotany in South Asia, J. K. Mahalakshmi, Ed., Scientific Publishers, Jodhpur, India, 1996. View at Google Scholar
  41. D. K. Mishra, G. Somanta, and T. K. Mishra, “Ethnomedicine of the tribe Kharia of Midnapore district, West Bengal,” in Ethnobotany in South Asia, J. K. Mahalakshmi, Ed., Scientific Publishers, Jodhpur, India, 1996. View at Google Scholar
  42. S. Pawar and D. A. Patil, “Ethnomedicinal uses of barks in Jalgaon district,” Natural Product Radiance, vol. 6, no. 4, pp. 341–346, 2007. View at Google Scholar · View at Scopus
  43. H. Singh, Medicinal Plants and Their Local Uses in Sub-Himalayan Tract of Uttaranchal, Medicinal Plants: Ethnobotanical Approach, Agrobios, Jodhpur, India, 2006, edited by P. C. Trivedi.
  44. M. J. Beg, M. Z. Beg, and S. J. Ali, Ethnomedicinal Studies on Sub-Himalayan Forest of North Eastern Utter Pradesh in Medicinal Plants: Ethnobotanical Approach, Agrobios, Jodhpur, India, 2006, edited by P. C. Trivedi.
  45. K. Hemamalini, S. Suvidha, A. Bhargav, and U. Vasireddy, “Evaluation of anti-ulcer activity of methanolic extracts of Kigelia africana, Sophara interrupta and Holoptelea integrifolia leaves in experimental rats,” International Journal of Current Pharmaceutical Research, vol. 4, pp. 16–21, 2012. View at Google Scholar
  46. G. H. Rizwani, S. Mahmud, H. Shareef, R. Perveen, and M. Ahmed, “Analgesic activity of various extracts of Holoptelea integrifolia (Roxb) Planch leaves,” Pakistan Journal of Pharmaceutical Sciences, vol. 25, pp. 629–632, 2012. View at Google Scholar
  47. K. Hemamalini and S. B. Sathya, “Hepatoprotective activity of Sophara interrupta and Holoptelea integrifolia against carbontetrachloride induced hepatotoxicity in rats,” International Journal of Biology Pharmacy and Allied Sciences, vol. 2, pp. 80–89, 2013. View at Google Scholar
  48. S. Singha, U. Adhikari, A. Ghosh, and G. Chandra, “Mosquito larvicidal potentiality of Holoptelea integrifolia leaf extract against Japanese Encephalitis Vector, Culex vishuni,” Journal of Mosquito Research, vol. 2, pp. 25–31, 2012. View at Google Scholar
  49. S. Shrinivas, K. Ravindra, M. Aradhana, and B. Kailash, “Ethanolic leaf extract of Holoptelea integrifolia Planch. decreases cisplatin-induced pica in rats,” Journal of Pharmacognosy, vol. 7, no. 16, pp. 293–297, 2008. View at Google Scholar · View at Scopus
  50. K. Hemamalini, L. G. Soujanya, U. Vasireedy, and P. Pavani, “CNS activity of the methanolic leaf extracts of Sophora interrupta Bedd, Kigelia pinnata Dc, Holoptelea integrifolia plants in experimental animal models,” International Journal of Pharmacy and Technology, vol. 3, pp. 3785–3791, 2011. View at Google Scholar
  51. A. K. Subhash and A. Augustine, “Hypolipidaemic effects of methanolic extract of Holoptelea integrifolia (Roxb.) Planchon bark in diet-induced obese rats,” Applied Biochemistry and Biotechnology, vol. 169, no. 2, pp. 546–553, 2013. View at Publisher · View at Google Scholar
  52. S. Mahmud, H. Shareef, M. Ahmad, S. Gouhar, and G. H. Rizwani, “Pharmacognostic studies on fresh mature leaves of Holoptelea integrifolia (ROXB) Planch,” Pakistan Journal of Botany, vol. 42, no. 6, pp. 3705–3708, 2010. View at Google Scholar · View at Scopus
  53. S. R. Kumar, C. Venkateshwar, G. Samuel, and R. S. Gangadhar, “Phytochemical screening of some compounds from leaf extracts of Holoptelea integrifolia (Planch.) and Celestrus emarginata (Grah.) used by Gondu tribes at Adilabad district, Andhra Pradesh, India,” International Journal of Engineering Science Invention, vol. 2, pp. 65–70, 2013. View at Google Scholar
  54. M. Ahmed, G. H. Rizwani, F. V. Mohammed, I. Mahmood, V. U. Ahmed, and S. Mahmud, “Triterpenoid antioxidant agents found in Holoptelea integrifolia (Roxb) Planch,” International Journal of Pharmaceutical, Chemical and Biological Science, vol. 3, pp. 63–67, 2013. View at Google Scholar