Adiponectin Levels Are Reduced While Markers of Systemic Inflammation and Aortic Remodelling Are Increased in Intrauterine Growth Restricted Mother-Child Couple
Table 2
Differences in examinations of blood values among the evaluated groups in maternal and fetal circulation. Data are presented as median and interquartile range (IQR). The value refers to Wilcoxon test.
IUGR (37)
SGA (33)
Controls (70)
Maternal blood
Adiponectin (µg/L)
45 (32–61)
58 (37–64)
57 (45–61)
(2)
Leptin (µg/L)
8.2 (5–11.9)
8.5 (5.2–10.7)
5.5 (3.1–7.6)
(2, 3)
Adiponectin/leptin
5.5 (2.7–8.7)
5.9 (4.6–12.5)
11.4 (7.1–18.1)
(2, 3)
IL-6 (ng/L)
4.9 (2.3–8.4)
3.9 (2.5–5.4)
4.6 (2.4–6.2)
NS
TNF (ng/L)
5.4 (4.3–10)
5.0 (4–5.6)
4.9 (4.0–6.1)
(1, 2)
CRP (mg/L)
5.1 (3.9–12.8)
4.1 (2.8–5.7)
4.9 (2.9–5.9)
(1, 2)
Fetal blood
Adiponectin (µg/L)
134 (105–159)
197 (122–239)
196 (134–239)
(1, 2)
Leptin (µg/L)
7.1 (5.5–8.3)
4.3 (2.7–7.8)
4.9 (2.9–6.5)
(1, 2)
Adiponectin/leptin
17.4 (14.3–24.2)
43.5 (24.4–75)
41.3 (31.1–79.7)
(1, 2)
IL-6 (ng/L)
8.6 (4.6–12.1)
5.3 (2.4–8.9)
4.7 (2.3–6)
(1, 2, 3)
TNF (ng/L)
11.1 (8.9–14.9)
8.3 (7.5–9.1)
8.7 (7.3–9.9)
(1, 2)
CRP (mg/L)
2.8 (2.7–2.9)
2.8 (2.7–2.9)
2.8 (2.8-2.9)
NS
Significant differences () between (1) IUGR and SGA; (2) IUGR and AGA; and (3) SGA and AGA. NS: nonsignificant differences.