Quercetin Significantly Inhibits the Metabolism of Caffeine, a Substrate of Cytochrome P450 1A2 Unrelated to (−2964G>A) and (734C>A) Gene Polymorphisms
Figure 4
Metabolic ratio of caffeine indicated by of paraxanthine (17X)/ of caffeine (137X) after a single oral dose of 100 mg caffeine on day 14 before and after 14-day quercetin treatment in GG/AA and GA/CA genotype groups. AUC, area under the plasma concentration-time curve, , .
