Attenuation of Collagen-Induced Arthritis in Mice by Salmon Proteoglycan
Figure 3
Administration of PG reduced cytokine expression in joints of CII-immunized mice. The expression of IL-17A (a), IL-6 (b), IL-1β (c), and IFN-γ (d) in joints was determined by quantitative real-time RT-PCR. Control, CII-PBS, and CII-PG indicate nonimmunized mice, CII-immunized mice administered with PBS, and CII-immunized mice administered with PG, respectively. Single asterisk () and double asterisk () indicate that the value is significantly different.
