Expression of Neuroendocrine Markers in Different Molecular Subtypes of Breast Carcinoma
Figure 2
Expression of specific (synaptophysin and chromogranin A) and non-specific (CD56, CD117) neuroendocrine markers in DCIS and invasive carcinoma. (a) Isolated chromogranin A positive cells in high-grade DCIS (inset: isolated synaptophysin positive cells in the same case). (b) High-grade DCIS with isolated CD56 positive cells. (c) High-grade DCIS diffusely expressing CD117. (d) Luminal B carcinoma NST diffusely expressing chromogranin A. (e) The same luminal B carcinoma is negative for synaptophysin. (f) Diffuse expression of CD56 in a triple-negative carcinoma.
