Research Article
A Preliminary Study of the Influence of Age of Onset and Childhood Trauma on Cortical Thickness in Major Depressive Disorder
Table 1
Characteristics of MDD onset groups (pediatric/adult MDD onset) and controls.
| | Characteristics | MDD (overall) | Pediatric MDD onset | Adult MDD onset | HC |
| | 36 | 20 | 16 | 18 | | Sex (F/M) | 22/14 | 12/8 | 10/6 | 10/8 | | Age (yrs.) | 37.1 ± 11.2 | 31.5 ± 10.5 | 44.1 ± 7.7 | 31.9 ± 9.2 | | Baseline HAMD17 | 22.1 ± 4.1 | 20.7 ± 4.1 | 23.9 ± 3.4 | — | | Duration of current MDE (yrs.) | 5.1 ± 5.4 | 4.9 ± 5.7 | 5.4 ± 5.3 | — | | Time since MDD onset (yrs.) | 12.3 ± 9.2 | 14.4 ± 10.7 | 9.8 ± 6.3 | — | | MDD onset (yrs.) | 24.8 ± 10.1 | 17.1 ± 4.8 | 34.3 ± 5.6 | — |
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HC: healthy controls; HAMD17: Hamilton Depression Rating Scale; MDD: major depressive disorder; MDE: major depressive episode; means ± SDs presented.
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