BioMed Research International / 2014 / Article / Tab 1

Review Article

Expression of Stem Cell and Epithelial-Mesenchymal Transition Markers in Circulating Tumor Cells of Breast Cancer Patients

Table 1

CTC detection and characterization markers.

MarkerReferenceCTC detection or enrichment markerEpithelial markerMesenchymal markerStem cell marker

Akt2[17, 19, 20]x
ALDH1[1720, 59, 64, 77, 78]x
Bmi1[19]x
CD133[18]x
CD24[18, 59, 77]x
CD44[18, 19, 59, 62, 77]x
Cytokeratins 8, 18, 19[24, 61]xx
E-cadherin (Cadherin 1)[69]x
EGFR[69]xx
EpCAM (GA733-2)[24, 58, 60, 61, 65, 69]xx
Fibronectin 1[69, 78]x
FoxC2[54, 74]x
HER2[60, 65, 69]xx
MUC1[60, 65]xx
N-cadherin (Cadherin 2)[69, 75]x
pan-Cytokeratin[59, 69]x
PI3K[17, 19, 20]x
SERPINE1/PAI1[69]x
SLUG[54, 74]x
SNAIL 1[18, 54, 74, 77]x
TG2[18]x
TWIST 1[1720, 54, 74, 76, 77]x
Vimentin[75, 76, 78]x
ZEB1[18, 54, 74]x
ZEB2[54]x

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