BioMed Research International / 2014 / Article / Tab 4

Review Article

Expression of Stem Cell and Epithelial-Mesenchymal Transition Markers in Circulating Tumor Cells of Breast Cancer Patients

Table 4

Stem cell markers in CTC of breast cancer patients.

AuthorYear MethodStem cell
marker
Expression rate in CTC

Kasimir-Bauer et al. [17]20125021RT-PCRALDH1 46%3, 5%4
Giordano et al. [18]2012282Flow cytometryALDH 
CD44+/CD24low
0.1% 
,
Barriere et al. [19]2012241RT-PCRALDH1 
CD44 
Bmi1
54% 
67%** 
33%**
Mego et al. [77]2012172Flow cytometryALDH 
CD44+/CD24low
n. d.
Raimondi et al. [78]2011611,2RT-PCRALDH146%
Aktas et al. [20]2009392RT-PCRALDH1 ,
Theodoropoulos et al. [59]2010302IFCALDH1 
CD44+/CD24low
18% 
35%

Primary breast cancer, 2metastatic breast cancer, 3CTC positive group, 4CTC negative group; *among ALDH positive cells, **among EMT or ALDH1 positive cells, n. d.: not done, IFC: immunofluorescence.

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