Bioinformatic Prediction of WSSV-Host Protein-Protein Interaction

Figure 1

A schematic diagram was drawn to describe the predicted protein-protein interactions between WSSV-CLP and membrane proteins from the shrimp and the intracellular signaling pathways induced by the interactions. The diagram was drawn based on the KEGG pathway map04510 (focal adhesion) and map04512 (ECM-receptor interaction). WSSV-CLP: WSSV collagen like protein; ITGA: integrin alpha; ITGB: integrin beta; SDC: syndecan; CCL5: chemokine ligand 5; PKC: protein kinase C; FAK: focal adhesion kinase; PI3K: phosphoinositide 3-kinase; FGF2: fibroblast growth factor 2; MMP7: matrix metalloproteinase-7.