DBC1/CCAR2 and CCAR1 Are Largely Disordered Proteins that Have Evolved from One Common Ancestor

Figure 4

Gapped disorder prediction for zDBC1, zCCAR1, and LST-3. The disorder prediction was analyzed by PONDR-FIT for zebrafish DBC1 (zDBC1, UniProt ID: E7FGT1), zebrafish CCAR1 (zCCAR1, UniProt ID: F1QV66), and C. elegans LST-3 (UniProt ID: G5EFJ2). Residues with a score higher than 0.5 on the -axis are disordered, while residues with score lower than 0.5 are structured. The -axis represents the amino acid number. The black line represents the disorder prediction, while the pink horizontal lines represent gapped segments. The shaded regions represent similar patterns seen between all three proteins.