DBC1/CCAR2 and CCAR1 Are Largely Disordered Proteins that Have Evolved from One Common Ancestor

Figure 7

The amino acid substitution rates of specific domains among various groups of species for DBC1 (a) and CCAR1 (b). Based on the sequences in Table  S1, human is in one group, all other primates excluding human are in the second group, all other Therapsida excluding primates are in the third group, all other mammals compose the fourth group, amphibians are in the fifth group, fish are in the sixth group, and insects are in the seventh group. Eight domains were analyzed including the S1-Like, NLS, LZ, SAP, CC1, EF-Hand, and CC2 domains.

(a)

(b)