Proteinases in Excretory-Secretory Products of Toxocara canis Second-Stage Larvae: Zymography and Modeling Insights
Figure 5
Protein modeling of T. canis excretory-secretory components (TES) and superimposition with homologs from other organisms ((a)-(b)) and between TES proteins with high (c) and low (d) structure homology. The following structures were superimposed using the I-Tasser platform coupled to the TM-align tool: (a) TcMUC4 (cartoon) and lipase with serine proteinase triad from Rhizomucor miehei (PDB 1TGL, backbone trace in purple); (b) TcTES26 (cartoon) and carboxypeptidase Y from S. cerevisiae (PDB 1WPX, backbone trace in purple); (c) TcTES32 (cartoon in blue) and TcTES70 (cartoon in red); (d) TES120/MUC1 (cartoon in blue) and TcMUC4 (cartoon in red).
