Are Proteinase 3 and Cathepsin C Enzymes Related to Pathogenesis of Periodontitis?

Table 3

GCF proteinase 3 and cathepsin C levels in sampling sites of the study groups (estimated mean ± SE [95% CI]).

	Healthy (𝑁=18)	Gingivitis (𝑁=20)	CP (𝑁=18)	G-AgP (𝑁=20)
PR3 (ng/sample)	1.91±0.23^∗	2.86±0.2	3.22±0.28	3.22±0.2
PR3 (ng/𝜇L)	14.39±1.8	10.41±1.7	9.02±2.11	11.49±1.7
CTSC (ng/sample)	0.25±0.30	0.81±1.2	0.3±0.25	0.8±0.97
CTSC (ng/𝜇L)	2.34±4.02	2.21±2.65	0.8±0.67	2.45±2.77

∗Significant difference from other groups.
CP: chronic periodontitis; G-AgP: generalized aggressive periodontitis; PR3: proteinase 3; CTSC: cathepsin C; SE: standard error.