Research Article

Designer Self-Assembling Peptide Nanofiber Scaffolds Containing Link Protein N-Terminal Peptide Induce Chondrogenesis of Rabbit Bone Marrow Stem Cells

Figure 8

Deposition of type II collagen in cells cultured on the RADA16 hydrogel (a1, a2, and a3) and functionalized LN-NS (b1, b2, and b3) at 14 days. Stained with Hoechst dye (a1 and b1) and FITC-conjugated anti-collagen II antibody (a2, b2), the cell nuclei had blue fluorescence, and type II collagen had green fluorescence. Immunofluorescence showed these cells on the functionalized LN-NS exhibited a higher differentiated level when compared with the pure RADA16 hydrogel.
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